Okay, let's take a look at this "Manny only fights fighters coming off losses" theory:
I'm just going to use Manny's notable fights as examples, starting with this:
Lehlohonolo Ledwaba (IBF Superbantamweight title) - 22 fight win streak
Marco Antonio Barrera - 8 fight win streak, including wins over Prince Naseem, Erik Morales, and Kevin Kelley
Juan Manuel Marquez (1st fight) - 13 fight win streak, with the last loss being a very questionable loss to Freddie Norwood. Another Joe Cortez classic fuckup.
Erik Morales (1st fight) - Fought Manny coming off a loss, though he did win the fight
Juan Manuel Marquez (2nd fight) - 4 fight win streak
Oscar de la Hoya - I don't put much into this fight, as it was more of a freakshow turned bad, but even then...Oscar was coming off a close win over Stevie Forbes
Ricky Hatton - 2 fight win streak, that included the most impressive performance of his career against Paulie Malignaggi
Miguel Cotto - 2 fight win streak, one close victory over top 5 welterweight Joshua Clottey
Joshua Clottey - Coming off a close loss to Miguel Cotto
Antonio Margarito - coming off loss to Shane Mosley, but I honestly don't see how you could hold that fight against him, he knew he was in deep shit, and his head clearly wasn't in this fight
I could see how you could point to his more recent welter/super welterweight fights, but the fact of the matter is that all of these top welterweights (Cotto, Clottey, Margarito, Mosley) were all doing what they were supposed to be doing which is fighting each other, so obviously someone's gotta lose.