Family Guy wouldnt exist without the Simpsons. That being said, I cant decide. I havent like the simpsons in 10 years. Simpsons is like the granddad of adult cartoon comedy. And i can see why some folks (coldblooded) dont like Family Guy, and its not the greatest show but it sure as hell has made me die laughing sometimes. Its fucking clever.
Also, south park is funny too but something that's always bothered me is that they're the most snobby of all the cartoons. fuck making fun of Family Guy for its random humor when South Park has pretty much survived on the same thing.