I think pretty much that no matter where you stay or what you do, it's going to be the same amount of money. If you plan on staying at X, you're going to still be paying the same for everything you do there... almost.
No place is going to be better than another. If you want to spend cash and have fun, you just spend cash and have fun. Vegas isn't a place to be cheap, for sure.
The first time I went there I was broke as fuck and had a GREAT time just drinking, eating and seeing what was around. Went to a few shows, which isn't really my scene but only spent about 250-300 and stayed drunk and had fun 24/7.
I should mention I don't gamble, I guess... so that factors in.