Selecus I. Nicator (312-281 B.C.) assumed the title of king in 306. He first subdued Upper Asia as far as the Indus and Jaxartes The battle of Ipsus brought Syria under his dominion; although he had to recognize the supremacy of Egypt over Phoenicia and Palestine. By a victory over Lysimachus he conquered the greater part of Asia Minor (281), but a little later, when he encroached on European territory, he was murdered by Ptolemy Ceraunus. Besides various other cities, Seleucus founded the magnificent residential towns of Seleucia on the Tigris and Antiochia on the Orontes.