As the top drug trafficker in Mexico, Carrillo was transporting four times more cocaine to the U.S. than any other trafficker in the world, building a fortune of over US$25 billion. He was called "El Señor de los Cielos" (The Lord of the Skies) for his pioneering use of over 27 private Boeing 727 jet airliners to transport Colombian cocaine to municipal airports and airstrips around Mexico.