Coronavirus

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RemyRoux

RemyRoux

Well-known member
#1
Sep 8, 2018
3,254
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#1
What do you need to know?

As of 23:59 Jan 31, there are officially:

Confirmed Cases: 9,171

Deaths: 213



5794 suspected cases in 30 provinces. 81947/88693 are under medical observation

170 deaths and 1370 are severe cases. 162/170 deaths occurred in Hubei province (where Wuhan is). The rest are within various provinces in China

  • 17 deaths range from 48-89 years old. 14/17 deaths are of the elderly above 65 years old. Most have pre-existing conditions that seem to predispose to a more severe disease presentation. People who are already sick prior to infection may be more at risk due to decreased immunity. Some of these people had hypertension, diabetes, and heart disease. Death was typically the result of severe respiratory failure but includes others like multi-organ failure. Info on some of the remaining deaths is currently unknown
  • Healthy people have died
  • 124 people recovered
90 exported cases: Thailand (14), Japan (11), Hong Kong/Singapore (10), Taiwan (8), Macao/Australia/Malaysia (7 each), USA/France (5 each), Germany/South Korea/UAE (4 each), Canada (3), Vietnam (2), Nepal/Cambodia/Finland/Sri Lanka (1 each)

Please refer to the live trackers for the most up-date statistics
Initial symptoms

  • cough
  • fever (pyrexia possible absence in young individuals)
  • fatigue, discomfort (malaise), shortness of breath (dyspnea), dizziness, chest tightness, headache, muscle aches, chills, sore throat
  • possible atypical presentations in immunosuppressed/elderly.
Treatment

No cure, care is supportive to relieve symptoms. Drugs and vaccines are being explored.

Rough Timeline of Some Key Events

Date 2019-nCoV Dec 1Earliest known patient with symptom onsetDec 24Collection of genomic sequence based on atypical pneumoniaDec 31WHO notifiedJan 1Seafood market is closed + decontaminatedJan 8Novel coronavirus identifiedJan 10Dr. Zhang (Shanghai) releases genome, first fatalityJan 131st exported case in ThailandJan 19First diagnostic testJan 20Human-Human transmission confirmedJan 23CEPI funding of vaccine development, quarantine beginsJan 28Australia is 1st to grow virus outside ChinaPresent/Onwardsanimal modeling, identification of reservoir, pathogenesis, pathophysiology etc

Some things healthcare professionals are doing + will do

  • Largest quarantine in the history of public health (~15 cities: with a combined population ~56 million)
  • Diagnostic testing: Molecular diagnostics, cell culture, microscopy, antigen/antibody detection, serosurveys
  • Genomic analyses: gives us an idea of drug targets, transmission, etc
  • vaccine development: at least 4 different vaccines confirmed,
  • Preparation of animal modeling: testing clinical manifestations etc
  • Epidemiological tracking: people at risk, super spreaders, R0 value etc
Some Insights
  • It shares a crucial protein with SARS. We're targeting this for drugs. Existing compounds are already being tested in China for treatment
  • Use of masks alone is insufficient to prevent infection. It can worsen problems if people believe all you need is a mask. Other hygiene measures are needed: wash hands, sneeze/coughing into a disposable tissue, maintain distance of >1 meter https://www.who.int/publications-de...of-the-novel-coronavirus-(2019-ncov)-outbreak
  • Incubation period for the first 425 patients was 5.2 days. R0 differs by study. If R0 > 1, the epidemic will increase. We aim to reduce this number to < 1. R0 = 2.2 so on average, each patient will infect 2.2 other people
  • Of the first 425 patients: 240 (56%) were male. No cases for children under age 15. 84 cases for ages 15-44. 179 cases between ages 45-64. 162 cases for age 65 and over. Incubation period for the first 425 patients was 5.2 days. Nearly half of cases occurred people over age 60. It's possible that children are infected but show milder symptoms. In the coming weeks, once developed, a seroprevalence study (where we test your blood serum) will give us a much better idea.
  • What we're monitoring is whether exportation of cases in other countries can sustain transmission. This is crucial leading up to a pandemic. Circulation within the community is bad news. It's why surveillance, isolation, and why close contacts are being monitored.
  • China does deserve some credit. If you compare the timeline with the SARS outbreak, we are doing way better (availability of data, transparency, measures of control, research etc). China hid reports of SARS and took 4 months to report to the WHO. It took 5 months to even identify it was a coronavirus and sequence the genome. We had a genome to analyze in lab within 11 days of their announcement to WHO. I remember laying in bed and jumping up when I was notified that the complete genome was available, pretty excited
  • I also want to stress that it is quite easy to sit behind a screen and throw blame around. Granted there are certain contributing factors leading to this outbreak but in my opinion, there is a time to address those. At the moment, there needs to be a focus on containment and research. If you're outside of China and worried about it, consider how it would feel to be in China. There are good people doing good work
Resources

★ = highly recommended

"Technical" resources - PUBLICLY AVAILABLE

 
StillHustlin

StillHustlin

MAC AVE LEE
#11
May 7, 2013
13,444
16,318
113
33°
www.hoescantstopme.biz
#11
killahoe925 said:
Only let South Korean females blow you. Much cleaner. They work with microchips and learned to be clean. Japanese as well. Chinese are dirty mofos.
Click to expand...
Chines work with microchips too lmao. Remember this one company I worked at a long time ago. The Singapore location didn't like to give techs breaks so one chic took a dump in the trashcan. How's that for a cleanroom lmao
💩
 
Props: RemyRoux and killahoe925
RemyRoux

RemyRoux

Well-known member
#12
Sep 8, 2018
3,254
2,828
113
#12
StillHustlin said:
Chines work with microchips too lmao. Remember this one company I worked at a long time ago. The Singapore location didn't like to give techs breaks so one chic took a dump in the trashcan. How's that for a cleanroom lmao
💩
Click to expand...
that's pretty bad lol

I remember a work lunch room, people sitting around eating and one chink goes up to the sink and hocks some spit, everyone was like what the fuck..
 
Props: StillHustlin
StillHustlin

StillHustlin

MAC AVE LEE
#14
May 7, 2013
13,444
16,318
113
33°
www.hoescantstopme.biz
#14
Current understanding about how the virus that causes coronavirus disease 2019 (COVID-19) spreads is largely based on what is known about similar coronaviruses.

Person-to-person spread
The virus is thought to spread mainly from person-to-person.

  • Between people who are in close contact with one another (within about 6 feet)
  • Via respiratory droplets produced when an infected person coughs or sneezes.
  • These droplets can land in the mouths or noses of people who are nearby or possibly be inhaled into the lungs.
Spread from contact with infected surfaces or objects
It may be possible that a person can get COVID-19 by touching a surface or object that has the virus on it and then touching their own mouth, nose, or possibly their eyes, but this is not thought to be the main way the virus spreads.

When does spread happen?
  • People are thought to be most contagious when they are most symptomatic (the sickest).
  • Some spread might be possible before people show symptoms; there have been reports of this with this new coronavirus, but this is not thought to be the main way the virus spreads.
How efficiently does the virus spread?
How easily a virus spreads from person-to-person can vary. Some viruses are highly contagious (like measles), while other viruses are less so. Another factor is whether the spread continues over multiple generations of people (if spread is sustained). The virus that causes COVID-19 seems to be spreading easily and sustainably in Hubei province and other parts of China. In the United States, spread from person-to-person has occurred only among a few close contacts and has not spread any further to date.

There is still more to be learned
COVID-19 is an emerging disease and there is more to learn about its transmissibility, severity, and other features and what will happen in the United States. New information will further inform the risk assessment.

Read the latest Coronavirus Disease 2019 (COVID-19), Wuhan, China situation summary.
 
StillHustlin

StillHustlin

MAC AVE LEE
#15
May 7, 2013
13,444
16,318
113
33°
www.hoescantstopme.biz
#15
Updated February 24, 2020
CDC is closely monitoring an outbreak of respiratory illness caused by a novel (new) coronavirus. The outbreak first started in Wuhan, China, but cases have been identified in a growing number of other international locations, including the United States. This page will be updated regularly on Mondays, Wednesdays, and Fridays.
COVID-19: Confirmed Cases in the United States*†
COVID-19: Confirmed Cases in the United States*†Travel-related12Person-to-person spread2Total confirmed cases 14Total tested 426
* This table represents cases detected and tested in the United States through U.S. public health surveillance systems since January 21, 2020. It does not include people who returned to the U.S. via State Department-chartered flights.
† Numbers closed out at 4 p.m. the day before reporting.
COVID-19: Cases among Persons Repatriated to the United States†
COVID-19: Cases among Persons Repatriated to the United States† Wuhan, China Diamond Princess Cruise Ship‡ Positive 336
† Numbers closed out at 4 p.m. the day before reporting.
‡ Cases have laboratory confirmation and may or may not have been symptomatic.


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NS Niner Ryda

Sicc OG
#20
Dec 18, 2015
314
486
63
#20
Santa clara county banning all events with 1,000 people or more for the rest of this month. I'm a Sharks season ticket holder and there's 3 games scheduled for this month all canceled. I better get a refund for those games.
 
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